Malaria: A comprehensive review of pathogenesis, clinical manifestations and current control methods
1 Department of Science, College of Basic Education _Shirqat, Tikrit University, Iraq.
2 Ministry of Education Directorate General of Salahuddin Education.
Review Article
Open Access Research Journal of Biology and Pharmacy, 2026, 17(01), 037-046.
Article DOI: 10.53022/oarjbp.2026.17.1.0039
Publication history:
Received on 14 May 2026; revised on 21 June 2026; accepted on 24 June 2026
Abstract:
Malaria is caused by protozoan parasites of the genus Plasmodium and is a main cause of mortality and morbidity worldwide. These parasites have a complex life cycle in their mosquito vector and vertebrate hosts. The primary factors contributing to the resurgence of malaria are the appearance of drug-resistant strains of the parasite, the spread of insecticide-resistant strains of the mosquito and the lack of licensed malaria vaccines of proven efficacy. This minireview includes a summary of the disease, the life cycle of the parasite, information relating to the genome and proteome of the species lethal to humans, Plasmodium falciparum, together with other recent developments in the field.
Keywords:
Malaria; Pathogenesis; Clinical Manifestations and Control Methods
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Copyright © 2026 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0